Mocetinostat

Overview
Catalog #	bs-82662c-5-mg
Product Name	Mocetinostat
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 μM for HDAC1, 2, 3 and 11 respectively.1 Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells.2 Displays antifibrotic effects in ischemic heart failure.3 Attenuates the development of hypersensitivity in models of neuropathic pain.4 Active in vivo.5
Description	CAS Number: 726169-73-9 Chemical Name: N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide Molecular weight: 396.44 Formula: C23H20N6O Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC, NMR (Conforms)