C-DIM 12

Overview
Catalog #	bs-82660c-5-mg
Product Name	C-DIM 12
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.1,2 Nurr1 is a suppressor of NFkB-related neuroinflammatory genes in microglia and astrocytes and C-DIM 12 suppresses inflammatory signaling in these cells.3 Displays neuroprotective activity in a mouse model of progressive neurodegeneration with a strong neuroinflammatory component (50 mg/Kg, oral).4
Description	CAS Number: 178946-89-9 Chemical Name: 3,3’-[(4-Chlorophenyl)methylene]bis[1H-indole] Molecular weight: 356.85 Formula: C23H17ClN2 Solubility: DMSO (35 mg/ml) Ethanol (35 mg/ml) Physical Properties: Orange solid Purity: 98% by TLC, NMR (Conforms)