Flavopiridol HCl

Overview
Catalog #	bs-82641c-5-mg
Product Name	Flavopiridol HCl
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.
Description	CAS Number: 131740-09-5 Chemical Name: 3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride Molecular weight: 438.30 Formula: C21H20ClNO5 HCl Solubility: DMSO (40 mg/ml) Water (40 mg/ml) Physical Properties: Light yellow solid Purity: 98% by HPLC, NMR (Conforms)