YM-58483

Overview
Catalog #	bs-82613c-5-mg
Product Name	YM-58483
Specifications
Storage Buffer	White or off-white solid
Storage Condition	-20°C
Target
Product Information	YM-58483 is a CRAC (calcium release-activated calcium) channel blocker1, a prototypic store-operated calcium channel2. Inhibits antigen-induced histamine release via modulation of mast cell responses.3 Displays potent analgesic actions in various pain models in mice and is orally active.4 Inhibits T cell-mediated immune responses in vivo.5
Description	CAS Number: 223499-30-7 Chemical Name: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide Molecular weight: 421.32 Formula: C15H9F6N5OS Solubility: DMSO (40 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms)