Reserpine
| Overview | |
| Catalog # | bs-82559c-1-g |
| Product Name | Reserpine |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson’s disease.5 |
| Description | CAS Number: 50-55-5 Chemical Name: (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Molecular weight: 608.68 Formula: C33H40N2O9 Solubility: DMSO (35 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |
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