2'-Deoxy-5-fluorocytidine
| Overview | |
| Catalog # | bs-82557c-5-mg |
| Product Name | 2'-Deoxy-5-fluorocytidine |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1. Like 5’-Azacytidine and decitabine, 2’-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation2. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways3. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo4. |
| Description | CAS Number: 10356-76-0 Chemical Name: 5-fluoro-2’deoxycytidine Molecular weight: 245.21 Formula: C9H12FN3O4 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms) |
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