Compound 115-7c
| Overview | |
| Catalog # | bs-82324c-5-mg |
| Product Name | Compound 115-7c |
| Specifications | |
| Storage Buffer | Orange solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4 |
| Description | CAS Number: 908074-72-6 Chemical Name: 4-(5-((Benzyloxycarbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid Molecular weight: 477.34 Formula: C23H22Cl2N2O5 Solubility: DMSO (20 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |
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