Nutlin-3
Overview | |
Catalog # | bs-82191c-5-mg |
Product Name | Nutlin-3 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p531. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells2-4. |
Description | CAS Number: 548472-68-0 Chemical Name: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one Molecular weight: 581.51 Formula: C30H30Cl2N4O4 Solubility: DMSO (50 mg/ml) Ethanol (50 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms) |