SP-600125

Overview
Catalog #	bs-82020c-10-mg
Product Name	SP-600125
Specifications
Storage Buffer	Yellow solid
Storage Condition	RT
Target
Product Information	Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50’s range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.
Description	CAS Number: 129-56-6 Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one Molecular weight: 220.23 Formula: C14H8N2O Solubility: DMSO (22 mg/ml) Ethanol (2 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC NMR conforms