ZM-336372

Overview
Catalog #	bs-82017c-5-mg
Product Name	ZM-336372
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2α) (IC50=2µM) and SAPK2β (p38β) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.
Description	CAS Number: 208260-29-1 Chemical Name: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide Molecular weight: 389.46 Formula: C23H23N3O3 Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR conforms