Tryptanthrin
| Overview | |
| Catalog # | bs-80455C |
| Product Name | Tryptanthrin |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:248.24 Formula:C15H8N2O2 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml) Chemical Name:Indolo(2,1-b)quinazoline-6,12-dione |
| Description | A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFκB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 μM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5 |
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