Gabexate mesylate
| Overview | |
| Catalog # | bs-80451C |
| Product Name | Gabexate mesylate |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:417.5 Formula:C16H23N3O4 • CH3SO3H Purity:>98% Solubility:Soluble in Water (up to at least 12 mg/ml) Chemical Name:4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester, monomethanesulfonate |
| Description | A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis.1 Reduces weight gain and improves metabol-ism in obese rodent models.2 In clinical use (in Japan) for pancreatitis.3 Inhibits influenza virus replication in human tracheal epithelial cells.4 Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.5 |
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