NSC95397

Overview
Catalog #	bs-80339C
Product Name	NSC95397
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:310.39 Formula:C14H14O4S2 Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 1 mg/ml). Chemical Name:2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
Description	A potent and selective inhibitor of Cdc25 phosphatase (Ki = 32, 96 and 40 nM for Cdc25A, B and C respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.1 Induces cell cycle arrest, phosphorylation of EGFR and activation of ERK-1 and -2.2 Inhibits carboxyl-terminal binding protein a transcriptional corepressor that suppresses multiple pro-apoptotic and epithelial genes.3 Induces eryptosis in human erythrocytes.4