TGN-020
Overview | |
Catalog # | bs-80331C |
Product Name | TGN-020 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:206.22 Formula:C8H6N4OS Purity:>98% Solubility:Soluble in DMSO (up to 10 mg/ml with warming) Chemical Name:N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide |
Description | Aquaporin 4 channel blocker, IC50 = 3.1 μM.1 Reduces ischemic cerebral edema in a mouse model of focal cerebral ischemia using MRI.2 Increases regional cerebral blood flow as determined in wild-type and AQP-4 knockout mice.3 Reduces brain edema when administered after onset of ischemia in rat models.4 |