DZNep

Overview
Catalog #	bs-80317C
Product Name	DZNep
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:298.7 Formula:C12H14N4O3 • HCl Purity:>98% Solubility:Soluble in DMSO (up to 40 mg/ml). Chemical Name:3-Deazaneplanocin A; (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-cyclopent-3-ene-1,2-diol, hydrochloride
Description	Potent histone methyltransferase inhibitor which decreases global histone methylation1. Inhibits trimethylation of H3K27 and H4K20 in vitro1. Selectively induces apoptosis in multiple cancer cell lines with no effect on normal cells2. May be used in cocktails to chemically induce pluripotent stem cells (CiPSCs) from somatic cells3. Enhances angiogenesis in a mouse model of limb ischemia4.