IQ-1S
| Overview | |
| Catalog # | bs-80308C |
| Product Name | IQ-1S |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:269.23 Formula:C15H8N3O ∙ Na Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml) Chemical Name:11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt |
| Description | JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric oxide release in vitro.1 Attenuates collagen-induced arthritis severity and inhibits murine delayed-type hypersensitivity in vivo.2 |
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