Pyocyanine

Overview
Catalog #	bs-80303C
Product Name	Pyocyanine
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:210.23 Formula:C13H10N2O Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml). Chemical Name:5-Methyl-1(5H)-phenazinone
Description	Pyocyanine, a redox-active phenazine produced by P. aeruginosa and other pathogens, is an electron receptor, which stimulates redox cycling in bacteria as well as in a variety of human cell lines. It enhances oxidative metabolism, which increases the formation of intracellular reactive oxygen species (ROS) via reduction of NADPH. Pyocyanine accelerates neutrophil apoptosis in vitro. Pyocyanine production by P. aeruginosa suppresses the acute inflammatory response by pathogen-driven acceleration of neutrophil apoptosis and associated reduction of local inflammation1,2.