IOX 1
| Overview | |
| Catalog # | bs-80249C |
| Product Name | IOX 1 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:189.17 Formula:C10H7NO3 Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml). Chemical Name:8-Hydroxy-5-quinolinecarboxylic acid |
| Description | Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively1. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling1. Cell permeable |
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