BRD-7389

Overview
Catalog #	bs-80247C
Product Name	BRD-7389
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:366.42 Formula:C24H18N2O2 Purity:>98% Solubility:Soluble in DMSO (up to 35 mg/ml). Chemical Name:1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione
Description	Inhibits p90 ribosomal S6 kinase (RSK), IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively1. Induces a beta-cell-like state in pancreatic apha-cells and induces insulin expression1,2. Increases the endocrine cell content and function of donor human pancreatic islets in culture1. Blocks muscarinic acetylcholine receptor-stimulated RSK activation and subsequent proliferation of SNU-407 colon cancer cells3.