Daminozide

Overview
Catalog #	bs-80233C
Product Name	Daminozide
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:160.17 Formula:C6H12N2O3 Purity:>98% Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming). Chemical Name:1-(2,2-Dimethylhydrazide)butanedioic acid
Description	A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.