LYS6K2

Overview
Catalog #	bs-80230C
Product Name	LYS6K2
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:445.42 Formula:C21H19F4N7 Purity:>98% Solubility:Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 3 mg/ml). Chemical Name:4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
Description	A selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.