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Trifluorothymidine

Overview
Catalog # bs-80163C
Product Name Trifluorothymidine
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:296.20

Formula:C10H11F3N2O5

Purity:>98%

Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)

Chemical Name:2’-Deoxy-5-trifluoromethyluridine

Description An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4