Phenylbutyrate Na
| Overview | |
| Catalog # | bs-80078C |
| Product Name | Phenylbutyrate Na |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:186.2 Formula:C10H11O2 • Na Purity:>98% Solubility:Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml). Chemical Name:4-Phenylbutyric acid, sodium salt |
| Description | Chemical chaperone for misfolded proteins1. Resolves ER stress in neuronal cells by aiding protein folding in the ER2. Counteracts impaired glucose homeostasis in a mouse model of type 2 diabetes by preventing islet amyloid formation3. Attenuates atherosclerotic progression and stabilizes existing plaques in mouse model of atherosclerosis via inhibition of ER stress4. Protects against amyloid β-induced neurotoxicity in a mouse model5. Weak histone deacetylase (HDAC) inhibitor which inhibits glioma cell proliferation6. Active in vivo. |
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