Thalidomide
Overview | |
Catalog # | bs-80075C |
Product Name | Thalidomide |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:258.25 Formula:C13H10N2O4 Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml). Chemical Name:N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic |
Description | Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic. |