VAS-2870

Overview
Catalog #	bs-80049C
Product Name	VAS-2870
Specifications
Storage Buffer	Powder
Storage Condition	RT
Target
Product Information	Molecular Weight:360.4 Formula:C18H12N6OS Purity:>98% Solubility:Soluble in DMSO (up to 10 mg/ml) or in DMF (up to 25 mg/ml). Chemical Name:3-Benyl-7-(2-benzoxazolyl)yhio-1,2,3-triazolo(4,5-d)pyrimidine
Description	NAD(P)H oxidase (Nox) inhibitor. Abolishes PDGF-mediated Nox activation and ROS production (100% at 10 M). Inhibits PMA-induced oxidative burst in HL-60 cells (IC50=2 µM). Enhances TGF-ß-induced apoptosis in liver tumor cells.