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MK-886

Overview
Catalog # bs-80027C
Product Name MK-886
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:472.08

Formula:C27H34ClNO2S

Purity:>98%

Solubility:Soluble in DMSO (up to 40 mg/ml).

Chemical Name:3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid

Description Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. Also inhibits PPARα (80% inhibition at 10 µM).3