MK-886
Overview | |
Catalog # | bs-80027C |
Product Name | MK-886 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:472.08 Formula:C27H34ClNO2S Purity:>98% Solubility:Soluble in DMSO (up to 40 mg/ml). Chemical Name:3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid |
Description | Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. Also inhibits PPARα (80% inhibition at 10 µM).3 |