SP-600125

Overview
Catalog #	bs-80021C
Product Name	SP-600125
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:220.23 Formula:C14H8N2O Purity:>98% Solubility:Soluble in DMSO (up to 22 mg/ml) or in Ethanol (up to 2 mg/ml). Chemical Name:Anthra[1-9-cd]pyrazol-6(2H)-one
Description	Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50’s range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.