Terreic acid

Overview
Catalog #	bs-75795c-1mg
Product Name	Terreic acid
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information	CAS Number: 121-40-4 Molecular formula: C7H6O4 Molecular weight: 154.1 Purity: >99% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml), EtOH, MeOH, acetone, DCM or water (1mg/ml, warming and sonication might be necessary). InChiKey: ATFNSNUJZOYXFC-RQJHMYQMSA-N SMILES: O=C([C@@H]1[C@H]2O1)C(C)=C(O)C2=O
Description	Mycotoxin. Antibacterial and anticancer agent. A cell-permeable quinone epoxide antibiotic. Covalent inhibitor of the bacterial enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA), which catalyzes the first committed step of bacterial cell wall biosynthesis. More potent than the known MurA inhibitor Fosphomycin. Reversible, substrate competitive and selective inhibitor of Bruton's tyrosine kinase (BTK) catalytic activity, an important factor in B-cell and mast cell activation. Shown to bind to the BTK pleckstrin homology domain (BTK-PH) and block the interaction between the BTK-PH and PKC, affecting the catalytic activity of BTK but not of PKC. Has minimal effect on Lyn, Syk, PKA, casein kinase I, ERK1, ERK2, and p38 kinase activities. Antioxidant.