Jak/Src Inhibitor 1 . hydrochloride

Overview
Catalog #	bs-75542c-1mg
Product Name	Jak/Src Inhibitor 1 . hydrochloride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 1332329-27-7 (parent) Molecular formula: C28H23ClF3N7O2 . HCl Molecular weight: 582.0 . 36.5 Purity: >97% (HPLC) Appearance: Yellow solid. Solubility: Soluble in DMSO. InChiKey: VQUNOHCOLZKQJY-UHFFFAOYSA-N SMILES: O=C(NC)C(C=C1)=CC=C1NC2=NC=C3C(CCN(C4=CC(NC(C5=NC=CC(C(F)(F)F)=C5)=O)=CC=C4Cl)C3)=N2.Cl
Description	Multi-kinase inhibitor with potent antiproliferative anti-migratory activities. Potent STAT3/5 inhibitor in vitro and in vivo. Combined inhibitor of key kinases phosphorylating STAT3 and STAT5 proteins such as JAK, SRC, ABL families of kinases, and class III/V receptor tyrosine kinases (RTK), including FLT3, c-KIT, CSF1-R, PDGFRs and VEGFRs, in nanomolar range.