PS-341 [Bortezomib]
Overview | |
Catalog # | bs-75509c-5mg |
Product Name | PS-341 [Bortezomib] |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 1 year after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 179324-69-7 Molecular formula: C19H25BN4O4 Molecular weight: 384.2 Purity: >97% (NMR) Appearance: White solid. Solubility: Soluble in DMSO, ethanol or methanol. Slightly soluble in water. InChiKey: GXJABQQUPOEUTA-RDJZCZTQSA-N SMILES: CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O |
Description | Highly potent, selective and reversible cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Anticancer compound. Inhibits proliferation and migration of several tumor cell lines with nanomolar potency. Apoptosis inducer. |