Rosiglitazone
Overview | |
Catalog # | bs-75481c-10mg |
Product Name | Rosiglitazone |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Stable for 2 years after receipt when stored at +4°C. Stock solutions are stable for 3 months when stored at -20°C. |
Target | |
Product Information | CAS Number: 122320-73-4 Molecular formula: C18H19N3O3S Molecular weight: 357.4 Purity: >98% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in DMSO, ethanol or methanol. InChiKey: YASAKCUCGLMORW-UHFFFAOYSA-N SMILES: CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1 |
Description | Antidiabetic, hypoglycemic agent [1, 5]. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist [2, 3]. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance [4-6, 8]. Improves blood pressure and vascular function [7]. Enhances proliferation of endogenous neural progenitor cells (NPCs) [9]. Anti-inflammatory compound [10, 11]. Has controversial therapeutic effects on the cardiovascular system [12]. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs) [13]. |