IBMX

Overview
Catalog #	bs-75437c-500mg
Product Name	IBMX
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 28822-58-4 Molecular formula: C10H14N4O2 Molecular weight: 222.3 Purity: >99% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO, ethanol or methanol. Insoluble in water. InChiKey: APIXJSLKIYYUKG-UHFFFAOYSA-N SMILES: CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O
Description	Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor [1, 5, 6, 11]. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis [9]. Enhances differentiation of 3T3-L1 cells [3]. Non-selective adenosine receptor antagonist [4]. Inhibits Ca2+ ion channels [7, 8]. Activates TNF-alpha [10]. Adipogenic [10]. Activates leukotriene synthesis [12]. Reduces inflammation and innate immunity [12].