C646
Overview | |
Catalog # | bs-75434c-1mg |
Product Name | C646 |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
Target | |
Product Information | CAS Number: 328968-36-1 Molecular formula: C24H19N3O6 Molecular weight: 445.4 Purity: >98% (NMR) Appearance: Red solid. Solubility: Soluble in DMSO (10mg/ml). InChiKey: HEKJYZZSCQBJGB-XDHOZWIPSA-N SMILES: CC1=NN(C(=O)\C1=C\C1=CC=C(O1)C1=CC(C)=C(C)C=C1[N+]([O-])=O)C1=CC=C(C=C1)C(O)=O |
Description | Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines. |