SAG

Overview
Catalog #	bs-75432c-1mg
Product Name	SAG
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information	CAS Number: 912545-86-9 Molecular formula: C28H28ClN3OS Molecular weight: 490.1 Purity: >98% (NMR) Appearance: Off-white to light yellow powder. Solubility: Soluble in DMSO. Sparingly soluble in water (acidification with HCl increases water solubility). InChiKey: VFSUUTYAEQOIMW-YHBQERECSA-N SMILES: [H][C@@]1(CC[C@@]([H])(CC1)N(CC1=CC=CC(=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1)NC
Description	Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.