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Bradykinin

Overview
Catalog # bs-75309c-5mg
Product Name Bradykinin
Specifications
Storage Buffer Powder
Storage Condition Stable for 1 year after receipt when stored at -20°C.
Target
Product Information CAS Number: 121283-65-6; 58-82-2 (free base)

Molecular formula: C50H73N15O11 . C2HF3O2

Molecular weight: 1060.2 . 114.0

Purity: >97% (HPLC)

Appearance: Lyophilized powder.

Solubility: Soluble in water (5mg/ml).

InChiKey: WTRZIOCXFWDHEM-MIEKKPBHSA-N

SMILES: [O-]C(=O)C(F)(F)F.N[C@@H](CCCNC([NH3+])=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Description Pro-inflammatory peptide, acting through G-protein-coupled receptors. Endogenous bradykinin receptor agonist that displays selectivity for B2 over B1 receptors. Endogenously formed following pathophysiological stimuli such as inflammation, tissue damage or anoxia. Activator of endothelial nitric oxide synthase (eNOS; NOS III). Reduces blood pressure by inducing the release of prostacyclin, nitric oxide and endothelium-derived hyperpolarizing factor. Plays an important role in the regulation of fluid and electrolyte balance, non-vascular smooth muscle contraction, vasodilation and capillary permeability.