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Z-Leu-Leu-Leu-B(OH)2 [MG-262]

Overview
Catalog # bs-75308c-200ug
Product Name Z-Leu-Leu-Leu-B(OH)2 [MG-262]
Specifications
Storage Buffer Powder
Storage Condition Stable for 1 year after receipt when stored at -20°C.
Target
Product Information CAS Number: 179324-22-2

Molecular formula: C25H42BN3O6

Molecular weight: 491.4

Purity: >95% (HPLC)

Appearance: Solid lyophilized powder.

Solubility: Soluble in DMSO.

InChiKey: MWKOOGAFELWOCD-FKBYEOEOSA-N

SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)B(O)O
Description Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Similar structure as MG-132 (AG-CP3-0011) but much higher potency.