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Dihydroartemisinin

Overview
Catalog # bs-75234c-50mg
Product Name Dihydroartemisinin
Specifications
Storage Buffer Solid
Storage Condition Stable for 1 year after receipt when stored at +4°C.
Target
Product Information CAS Number: 71939-50-9

Molecular formula: C15H24O5

Molecular weight: 284.3

Purity: >98% (HPLC)

Appearance: White solid.

Solubility: Soluble in DMSO or ethanol.

InChiKey: BJDCWCLMFKKGEE-ISOSDAIHSA-N

SMILES: [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(O[C@H](O)[C@@H]2C)O4
Description Active metabolite of artemisinin. Anti-malaria (Plasmodium). Anti-schistosoma. Apoptosis inducer. Anti-cancer. Anti-inflammatory Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Autophagy inducer. Functional ARX inhibitor. Enhancer of GABAA signalling. Targets Gephyrin. Sown to have anti-SARS-CoV-2 activity with an EC50 of 13.31 ± 1.24µM, and beeing potentially useful in the treatment of COVID-19.