PF-06952229

Overview
Catalog #	bs-6894c-10mg-solid
Product Name	PF-06952229
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 458.91 Formula: C23 H24 Cl F N4 O3 CAS Number: 1801333-55-0 InChi Key: IPBLCOKXDQHSQW-UHFFFAOYSA-N InChi: InChI=1S/C23H24ClFN4O3/c1-13(2)17-10-27-21(16-7-14(24)3-4-19(16)25)8-22(17)29-20-5-6-26-9-18(20)23(32)28-15(11-30)12-31/h3-10,13,15,30-31H,11-12H2,1-2H3,(H,28,32)(H,26,27,29) Smiles: CC(C)C1=CN=C(C=C1NC1=CC=NC=C1C(=O)NC(CO)CO)C1C=C(Cl)C=CC=1F Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction. PF-06952229 is a promising antineoplastic agent for the study solid tumors, especifically metastatic breast cancer.