A83-01 --- an ALK inhibibitor.

Overview
Catalog #	bs-6893c-10mg-solid
Product Name	A83-01 --- an ALK inhibibitor.
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 421.52 Formula: C25 H19 N5 S CAS Number: 909910-43-6 InChi Key: HIJMSZGHKQPPJS-UHFFFAOYSA-N InChi: InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31) Smiles: CC1=CC=CC(=N1)C1=NN(C=C1C1=CC=NC2=CC=CC=C12)C(=S)NC1C=CC=CC=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: white solid powder Shelf Life: 2.0 years
Description	A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity induced by TGF-beta type I receptor ALK-5 and that by activin type IB receptor ALK-4 and nodal type I receptor ALK-7, the kinase domains of which are structurally highly related to those of ALK-5.