SC-79

Overview
Catalog #	bs-6552c-2mg-solid
Product Name	SC-79
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 364.78 Formula: C17 H17 Cl N2 O5 CAS Number: 305834-79-1 InChi Key: DXVKFBGVVRSOLI-UHFFFAOYSA-N InChi: InChI=1S/C17H17ClN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3 Smiles: CCOC(=O)C1C(C(C#N)C(=O)OCC)C2=CC(Cl)=CC=C2OC=1N Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	SC-79 is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head. SC-79 injections inhibited alcohol-induced osteonecrosis. Alcohol-induced ONFH is associated with suppression of p-Akt-Ser473 in the Akt/GSK3β/β-catenin signaling pathway in bone mesenchymal stem cells.