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GSK-3787

Overview
Catalog # bs-6404c-2mg-solid
Product Name GSK-3787
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 392.78

Formula: C15 H12 Cl F3 N2 O3 S

CAS Number: 188591-46-0

InChi Key: JFUIMTGOQCQTPF-UHFFFAOYSA-N

InChi: InChI=1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23,24)13-6-3-11(9-21-13)15(17,18)19/h1-6,9H,7-8H2,(H,20,22)

Smiles: O=C(NCCS(=O)(=O)C1C=CC(=CN=1)C(F)(F)F)C1C=CC(Cl)=CC=1

Purity: 98.0

Solubility: soluble in DMSO, not soluble in water.

Appearance: Solid Power

Shelf Life: 1.0 years
Description GSK-3787 is a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist with good pharmacokinetic properties. GSK3787 can antagonize PPARbeta/delta in vivo, thus providing a new strategy to delineate the functional role of a receptor with great potential as a therapeutic target for the treatment and prevention of disease.