Pyridostatin TFA salt

Overview
Catalog #	bs-6403c-10mg-solid
Product Name	Pyridostatin TFA salt
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 938.71 Formula: C37 H35 F9 N8 O11 CAS Number: 1085412-37-8 InChi Key: CYYZQGUDHAKBIQ-UHFFFAOYSA-N InChi: InChI=1S/C31H32N8O5.3C2HF3O2/c32-9-12-42-19-15-24(30(40)38-28-17-26(43-13-10-33)20-5-1-3-7-22(20)36-28)35-25(16-19)31(41)39-29-18-27(44-14-11-34)21-6-2-4-8-23(21)37-29;33-2(4,5)1(6)7/h1-8,15-18H,9-14,32-34H2,(H,36,38,40)(H,37,39,41);3(H,6,7) Smiles: NCCOC1C=C(N=C(C=1)C(=O)NC1C=C(OCCN)C2=CC=CC=C2N=1)C(=O)NC1C=C(OCCN)C2=CC=CC=C2N=1.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets gene bodies containing clusters of sequences with a propensity for G-quadruplex formation. As a result, pyridostatin modulated the expression of these genes, including the proto-oncogene SRC.