GLPG0634

Overview
Catalog #	bs-60418c-2mg-solid
Product Name	GLPG0634
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 425.5 Formula: C21 H23 N5 O3 S CAS Number: 1206161-97-8 InChi Key: RIJLVEAXPNLDTC-UHFFFAOYSA-N InChi: InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27) Smiles: O=C(NC1N=C2C=CC=C(C3C=CC(CN4CCS(=O)(=O)CC4)=CC=3)N2N=1)C1CC1 Purity: 98.0 Solubility: Solubility (25°C) DMSO: 85 mg/mL(199.76 mM). Water: Insoluble. Appearance: Solid Power. Shelf Life: 1.0 years
Description	GLPG0634 is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.