BAF312 --- S1P1/5 Selective Agonist
| Overview | |
| Catalog # | bs-60039c-2-mg-solid |
| Product Name | BAF312 --- S1P1/5 Selective Agonist |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 516.6 Formula: C29 H35 F3 N2 O3 CAS Number: 800379-64-0 InChi Key: KIHYPELVXPAIDH-HNSNBQBZSA-N InChi: InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+ Smiles: C/C(=N\OCC1=CC(=C(C=C1)C1CCCCC1)C(F)(F)F)/C1C=CC(CN2CC(C2)C(O)=O)=C(CC)C=1 Purity: 98.0 Solubility: DMSO up to 20mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | BAF312 is a next-generation potent sphingosine 1-phosphate (S1P) receptor agonist, selective for S1P1 (EC50 ~0.39 nM) and S1P5 (EC50 ~0.98 nM). As S1P1 plays a central role in lymphocyte egress from lymph nodes and is a validated drug target in immune-mediated diseases, BAF312 is currently in clinical trials to treat multiple sclerosis. |
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