Y-27632 --- Rock Inhibitor.
| Overview | |
| Catalog # | bs-60011c-2mg-solid |
| Product Name | Y-27632 --- Rock Inhibitor. |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 247.34 Formula: C14 H21 N3 O CAS Number: 146986-50-7 InChi Key: IYOZTVGMEWJPKR-IJLUTSLNSA-N InChi: InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1 Smiles: C[C@@H](N)[C@@H]1CC[C@H](CC1)C(=O)NC1C=CN=CC=1 Purity: 98.0 Solubility: DMSO up to 100mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | Y-27632 is a widely used, selective inhibitor of the Rho-associated protein kinase p160ROCK with a Ki value at ~ 0.14 μM. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self-renewal properties, including hESC/iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. |
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