Thiazovivin --- Rock Inhibitor
| Overview | |
| Catalog # | bs-60009c-25mg-solid |
| Product Name | Thiazovivin --- Rock Inhibitor |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 311.36 Formula: C15 H13 N5 O S CAS Number: 1226056-71-8 InChi Key: DOBKQCZBPPCLEG-UHFFFAOYSA-N InChi: InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20) Smiles: O=C(NCC1C=CC=CC=1)C1=CSC(NC2C=CN=CN=2)=N1 Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | Thiazovivin is a highly potent, selective, and cell-permeable small molecule Rock inhibitor with effective cellular activity ~ 2 μM. It can enhance survival of human embryonic stem cells (hESCs) or iPSCs after single cell dissociation by trypsin, and dramatically improve the reprogramming efficiency of iPSC (>200 folds) from human fibroblasts when used in combination with SB431542 and PD0325091. It has been shown to exhibit better activity than Y27632 in many stem cell assays. |
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