Chromodomain helicase DNA binding 4 Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
| Overview | |
| Catalog # | bsm-90046R |
| Product Name | Chromodomain helicase DNA binding 4 Monoclonal Antibody + Cell Lysate Kit |
| Applications | WB, FCM, IC |
| Specificity | Knockdown Validated |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human CHD4 |
| Immunogen Range | 1800-1870/1912 |
| Clonality | Monoclonal |
| Clone # | 23GB1310 |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Affinity Purified |
| Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage Condition | -20 °C |
| Target | |
| Gene ID | 1108 |
| Swiss Prot | Q14839 |
| Synonyms | CHD3; Chromodomain Helicase DNA Binding Protein 4; Chromodomain-Helicase-DNA-Binding Protein 4; Mi-2 Autoantigen 218 KDa Protein; ATP-Dependent Helicase CHD4; Mi2-BETA; Mi-2b; CHD-4; EC 3.6.4.12; MI2-BETA; Mi2-Beta; EC 3.6.1; SIHIWES; MI-2B |
| Background | ATP-dependent helicase that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Cell Line: HeLa Knockdown technology: shRNA Knockdown |
| Application Dilution | |
| WB | : 1:1000-1:5000 |
| FCM | FCM: 1:2000 |
| IC | IC: 1:1000 |
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