Complement C3 Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
| Overview | |
| Catalog # | bsm-90042R |
| Product Name | Complement C3 Monoclonal Antibody + Cell Lysate Kit |
| Applications | WB, IC |
| Specificity | Knockdown Validated |
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human C3 / C3a |
| Immunogen Range | 850-900/1663 |
| Clonality | Monoclonal |
| Clone # | 23GB1285 |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Affinity Purified |
| Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage Condition | -20 °C |
| Target | |
| Gene ID | 718 |
| Swiss Prot | P01024 |
| Synonyms | C1QBP; Complement C3; CPAMD1; ARMD9; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; Complement Component C3a; Complement Component C3b; Complement Component 3; C3a Anaphylatoxin; Prepro-C3; C3a; C3b; Epididymis Secretory Sperm Binding Protein Li 62p; Acylation-Stimulating Protein Cleavage Product; HEL-S-62p; AHUS5; ASP; C3A; C3B |
| Background | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Cell Line: HeLa Knockdown technology: shRNA Knockdown |
| Application Dilution | |
| WB | : 1:1000-1:5000 |
| IC | IC: 1:1000 |
Powered by Bioz