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IDH1 Monoclonal Antibody + Cell Lysate Kit

Applications

  • WB
  • FCM
  • IC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-90019R
Product Name IDH1 Monoclonal Antibody + Cell Lysate Kit
Applications WB, FCM, IC
Specificity Knockdown Validated
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source A synthesized peptide derived from human IDH1
Immunogen Range 1-70/414
Clonality Monoclonal
Clone # 23GB2105
Isotype IgG
Concentration Lot dependent
Purification Affinity Purified
Storage Buffer Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Storage Condition -20 °C
Target
Gene ID 3417
Swiss Prot O75874
Synonyms IDH1; Isocitrate Dehydrogenase (NADP(+)) 1; Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic; Isocitrate Dehydrogenase 1 (NADP+), Soluble; Isocitrate Dehydrogenase [NADP] Cytoplasmic; Oxalosuccinate Decarboxylase; NADP(+)-Specific ICDH; EC 1.1.1.42; PICD; IDH; NADP-Dependent Isocitrate Dehydrogenase, Peroxisomal; NADP-Dependent Isocitrate Dehydrogenase, Cytosolic; Epididymis Secretory Sperm Binding Protein; Cytosolic NADP-Isocitrate Dehydrogenase; Isocitrate Dehydrogenase 1 (NADP+); Epididymis Secretory Protein Li 26; Epididymis Luminal Protein 216; HEL-S-26; HEL-216; IDCD; IDPC; IDPc; IDP
Background Catalyzes the NADP+-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity)..

Cell Line: HeLa

Knockdown technology: shRNA Knockdown
Application Dilution
WB : 1:1000-1:5000
FCM FCM: 1:2000
IC IC: 1:1000