Diaphanous related formin 1 Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
| Overview | |
| Catalog # | bsm-90008R |
| Product Name | Diaphanous related formin 1 Monoclonal Antibody + Cell Lysate Kit |
| Applications | WB, FCM, IC |
| Specificity | Knockdown Validated |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human DIAPH1 |
| Immunogen Range | 1-45/1272 |
| Clonality | Monoclonal |
| Clone # | 23GB1990 |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Affinity Purified |
| Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage Condition | -20 °C |
| Target | |
| Gene ID | 1729 |
| Swiss Prot | O60610 |
| Synonyms | DIAPH1; Diaphanous Related Formin 1; HDIA1; LFHL1; Mammalian Diaphanous Related Formin 1; Protein Diaphanous Homolog 1; MDia1; DFNA1; DRF1; Diaphanous (Drosophila, Homolog) 1; Diaphanous Homolog 1 (Drosophila); Diaphanous-Related Formin-1; SCBMS; MDIA1; DIAP1; DIA1 |
| Background | Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers (By similarity). Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization (By similarity). Required for cytokinesis, and transcriptional activation of the serum response factor (By similarity). DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity). Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration (By similarity). Has neurite outgrowth promoting activity. Acts in a Rho-dependent manner to recruit PFY1 to the membrane (By similarity) .Cell Line: Hela Knockdown technology: shRNA Knockdown |
| Application Dilution | |
| WB | : 1:1000-1:5000 |
| FCM | FCM: 1:2000 |
| IC | IC: 1:1000 |
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